In 2017, we were in our 30’s, living in Chicago, working our dream jobs and raising our two year old daughter while expecting our second baby. On the day we brought our second daughter home from the hospital, I was told I had ALS by a general neurologist and he told me I had six months to live. The appointment lasted all of ten minutes.
Over the next several months, we saw six different ALS specialists in a desperate attempt to find out if he was wrong. With each new specialist, we ended up having to repeat the same test over and over again. We had to fight for basic testing, including genetic testing, and were left on our own to research every clinical trial and therapy as these clinicians were often unaware of them.
In 2019, we launched I AM ALS, a patient-centric, patient-led nonprofit dedicated to rewriting the ALS story, which has grown to a community of over 50,000. Through I AM ALS, we met countless patients who told the same story about their diagnosis and care journey.
This same patient-centric spirit of change and empowerment animates everything we do at Synapticure. Neurodegenerative disease care today is hard. It should not be. It should be easy and accessible to everyone. It is time to leave behind the era of “I’m sorry but we can’t help you.”
Brian Wallach & Sandra Abrevaya
ALS Patient & ALS Caregiver
Co-Founder, Chief Executive Officer
Sandra Abrevaya, ALS caregiver, Co-Founder and CEO of Synapticure, a specialty telehealth clinic transforming the experience & outcomes of neurodegenerative disease for patients and caregivers across the U.S. Prior to Sandra’s husband's diagnosis with ALS in 2017, she served in senior roles in the U.S. House, U.S. Senate, the U.S. Department of Education and as Associate Communications Director in the Obama White House. Since their diagnosis, Sandra and her husband Brian co-founded I AM ALS to drive an impactful advocacy agenda that has resulted in two bills becoming law and increasing federal funding for ALS by over $600 million. Sandra received her BA from the University of Michigan and her JD from Northwestern University.
Co-Founder, Chief Executive Officer
Co-Founder, Board Co-Chair
Brian Wallach, ALS patient, Co-Founder and Board-Co-Chair of Synapticure, a specialty telehealth clinic transforming the experience & outcomes of neurodegenerative disease for patients and caregivers across the U.S. Brian was diagnosed with ALS in November 2017 and since then has become an outspoken, well-known and impactful patient advocate in the neurodegenerative disease space. In addition to co-founding the nonprofit I AM ALS, Brian was an Assistant United States Attorney in the Northern District of Illinois and Senior Vetting Counsel in the Obama White House. Brian received his BA from Yale University and his JD from the Georgetown University Law Center.
Co-Founder, Board Co-Chair
Chief Operating Officer
As Chief Operating Officer, Joe is responsible for growth and operations, including scaling Synapticure’s care model to serve individuals and caregivers nationwide who are living with neurodegenerative diseases, and structuring partnerships with payers and providers to improve costs and outcomes.
Joe’s career has focused on building and operating health tech start-ups. He was most recently GM and Head of Market Development at Cityblock Health, providing technology-enabled primary care, behavioral health and social care to Dual Eligibles and individuals with Medicaid. He was previously Managing Director of Strategy and Transformation at Evolent Health, working with health systems and primary care providers to deliver value-based care for seniors. He started his career with Deloitte Consulting. Joe received his BA from the University of Pittsburgh and MS from Carnegie Mellon University. He lives in Alexandria, VA.
Chief Operating Officer
Co-Founder, Chief Financial Officer, Board Member
Peter entered the healthcare space after Brian’s diagnosis, originally focusing on investing in targeted therapeutics that had the potential to be truly disease altering in ALS. With Synapticure, Peter hopes to resolve the lack of early intervention, access to quality care, holistic patient data and clear subgrouping of people living with ALS. These shortcomings of the current system have hindered the success of ALS trials broadly and made it difficult to bring forward drugs that focused on specific subsets of the ALS patient population and could better the lives of all people living with ALS.
Prior to working to help solve ALS, Peter worked in the cleantech industry before becoming a consultant at Bain & Company in their Chicago office. Peter received his MBA from Columbia University and undergraduate degree from The University of Virginia.
Co-Founder, Chief Financial Officer, Board Member
Senior Medical Advisor
Dr. Andrews has over 15 years of experience caring for people with neuromuscular disorders, primarily Amyotrophic Lateral Sclerosis. In addition, she has extensive experience conducting and overseeing clinical trials in both the academic and industry setting and has held several leadership positions in organizations that focus on ALS clinical trials and care.
Dr. Andrews received B.S. from Union College, M.Sc. in Biostatistics (Patient-Oriented Research) from Columbia University's Mailman School of Public Health, and M.D. from Albany Medical College. Dr. Andrews completed her residency in Neurology at the University of Connecticut and completed fellowship training in both Neuromuscular Medicine and Clinical Neurophysiology at Columbia University. Dr. Andrews is board certified in Neurology, Neuromuscular Disease, and Electrodiagnostic Medicine.
Senior Medical Advisor
Co-Founder, Board Co-Chair
Jason Langheier, MD, MPH, is the CEO and Founder of Foodsmart – the leading provider of telenutrition and value-based foodcare -- making eating well simple and affordable for millions of Americans. Dr. Langheier did neuroscience, genetics and bioinformatics research at Williams, Duke, Cambridge and NIH, and received his MD from Duke, and his MPH from Harvard. Applying behavioral neuroscience and nutritional epidemiology training, he developed the pediatric obesity clinic at Boston Medical Center (Nutrition & Fitness for Life), Fitness Forward and the Coach K Drive 2 Fitness. He was the CTO and Co-Founder of Proventys (now US Oncology/ McKesson), collaborating with the National Comprehensive Cancer Network to deliver personalized cancer care decision support. He is an active member of the Partnership for a Healthier America (PHA) Board of Directors, and loves hiking, playing sports and music with family and friends.
Co-Founder, Board Co-Chair
Co-Founder, Board of Advisors Chair
Jonathan Hirsch is a company founder, investor, and advisor at the intersection of healthcare, life sciences, and data. Jonathan founded Syapse in 2008, and during more than a decade of building the company, Jonathan defined and implemented a vision for transforming cancer care through precision medicine and real world evidence. Jonathan serves on the Advisory Boards of companies including Freenome, VizAI, and PaigeAI, and has helped shape the regulatory use of real world evidence through creating and serving as Principal Investigator for a Research Collaboration with the FDA. Jonathan has catalyzed national cancer data sharing networks, including serving on the White House Cancer Moonshot Data Sharing Working Group. As both an active investor and partner in venture funds, including the Kleiner Perkins seed fund and Rebel Fund, Jonathan has incubated and invested in dozens of companies at the intersection of healthcare and technology.
Co-Founder, Board of Advisors Chair
Head of Product
Christie Byrne is the Head of Product at Synapticure. She previously worked at Cricket Health, a start-up focused on early-intervention for chronic kidney disease patients, where she oversaw development of clinical products. Prior to transitioning into the digital health sector, Christie worked in clinical research at the Parkinson’s Institute, as well as at UCSF in the Memory and Aging Center, where she helped lead Care Ecosystem, a study designed to expand access to dementia patients via a remote care model. Having studied behavioral neuroscience in college, and after watching multiple family members battle neurodegenerative diseases, she feels a sense of urgency to help patients gain access to personalized, life-saving treatments, and is passionate about making that world a reality at Synapticure.
Head of Product
Interim Chief Technology Officer
Graham is the Interim Chief Technology Officer at Synapticure, and a managing partner at GV. He was an engineering director at Google following the 2006 acquisition of JotSpot, which he co-founded with Joe Kraus. Graham was one of the original six founders of Excite.com and was the chief technology officer of the company until its sale to @Home. In 1999, Graham left Excite@Home to co-found DigitalConsumer.org, a 50,000-member non-profit consumer organization dedicated to protecting fair-use rights for digital media.
Interim Chief Technology Officer
Product and Technology Advisor
Geoffrey Clapp has been involved with digital health before it was called digital health. As a founder, operator, and investor Geoff has helped lead and guide some of the most important and influential companies to fuse healthcare and technology. At Synapticure he is a partner to the leadership team and key advisor on technology and product directions. He is currently the SVP of Renal Care and Transplant for Optum.
Product and Technology Advisor
VP of Clinical Operations and Care Delivery
VP of Clinical Operations and Care Delivery
VP of Science
Aaron Gitler is the Stanford Medicine Basic Science Professor in the Department of Genetics at Stanford University. He received his B.S. degree from Penn State University and did his PhD studies on cardiovascular development in the laboratory of Dr. Jonathan Epstein at the University of Pennsylvania. Then he performed his postdoctoral training with Dr. Susan Lindquist at the Whitehead Institute for Biomedical Research and MIT. In 2007, he established his laboratory at the University of Pennsylvania and moved to Stanford in 2012. His laboratory has been using a combination of yeast and human genetics approaches to investigate pathogenic mechanisms of ALS. He and his colleagues discovered mutations in the ATAXIN2 gene as a genetic contributor to ALS and has identified several therapeutic targets for ALS. He is a scientific co-founder of Maze Therapeutics
VP of Science
Stanford Anesthesia Digital Health Lead
Advisor
Digital Health Expert, Adjunct Professor and Member of the Board of Advisors, College of Public Health, George Mason University
Deputy Chief Scientific Officer of Barrow Neurological Institute
Data and Product Strategy Advisor
Founder and CEO of Perlara
Director, Robert Packard Center for ALS Research at John Hopkins Medicine
Chair of Neurology, Senior Vice President, Barrow Neurological Institute
John Douglas French Foundation Endowed Professor of Stem Cell Biology and Regenerative Medicine, University of Southern California
Managing Partner, Venture Valkyrie, Faculty, Haas School of Business, UC Berkeley
Board of Directors, Unite US
Director, Michigan Brain Bank and Neurology Associate Professor at University of Michigan Medical School
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